Disclaimer: I did both an S2ki search and a google search for this code before posting and I couldn't find anything.

My 2001 S2000 popped a CEL this morning. I had it scanned at AutoZone and they told me that it was typically the code for a vacuum leak.

Has anyone else had this code? How should I diagnose it?

 

Look for vacuum leaks loose connections and proper routing. Blow smoke into the engine with a party smoke machine and look where smoke comes out, there's your leak.